Elizabeth L. Wagner
Technical Specialist
Alexandria, VA
(703) 836-6400
Beth Wagner is a Technical Specialist with the firm, where she focuses on the prosecution of patent applications in a wide range of subject matter, including pharmaceuticals and biotechnology. Beth has several years of experience assisting clients with a variety of matters including application drafting, U.S. and foreign prosecution, freedom-to-operate and patentability searching, and Patent Trial & Appeal Board (PTAB) proceedings.
Prior to transitioning to the intellectual property field, Beth received her Ph.D. in Biochemistry & Molecular Genetics from the University of Virginia in the lab of Jung-Bum Shin, which studies the molecular basis of hearing and hearing loss. Her dissertation research focused on the characterization of a protein responsible for the maintenance and repair of inner ear hair cells using a variety of tools including gene editing, gene therapy, microscopy, and protein biochemical analysis. She earned her M.S. in Biological & Physical Sciences from the University of Virginia and her B.S. in Genetics and B.S. in Biochemistry from Clemson University, graduating summa cum laude.
Wagner, E.L., …, Shin, J.B. (2023) Repair of Noise-Induced Damage to Stereocilia F-Actin Cores is Facilitated by XIRP2 and Its Novel Mechanosensor Domain. Elife, 12:E72681. DOI: 10.7554/Elife.72681.
Wengert, E.R., Wenker, I.C., Wagner, E.L., …Shin, J.B., and Patel, M.K. (2021) Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of SCN8A Encephalopathy. Front. Neurosci. 15:198. DOI: 10.3389/fnins.2021.581048
Li, S., Mecca, A., Kim, J., Wagner, E.L., …, Shin, J.B. (2020) Myosin-VIIa is Expressed in Multiple Isoforms and Essential for Tensioning the Hair Cell Mechanotransduction Complex. Nat. Commun. 11, 2066. DOI: 10.1038/S41467- 020- 15936-Z
Ruhl, D., Du, T.T., Wagner, E.L., …, Hashasaki, G., Lukens, J.R., and Shin, J.B. (2019) Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity. J. Neurosci. 39 (15):2951-2964.
Wagner, E.L. and Shin, J.B. (2019) Mechanisms of Hair Cell Damage and Repair. Trends Neurosci. DOI: 10.1016/j.tins.2019.03.006
Du, T.T., Dewey, J.B., Wagner, E.L., …, Shin, J.B. (2019) LMO7 Deficiency Reveals the Significance of the Cuticular Plate for Hearing Function. Nat. Commun. 10 (1):1-15
Nicholas, B.D., Francis, S., Wagner, E.L., Zhang, S., and Shin, J.B. (2017) Protein Synthesis Inhibition and Activation of the C-Jun N-Terminal Kinase are Potential Contributors to Cisplatin Ototoxicity. Front. Cell. Neurosci. 11:303. DOI: 10.3389/Fncel.2017.00303
Lyda, T., Wagner, E.L., …, and Marcotte, Jr, W.(2017) A Leishmania Secretion System for the Expression of Major Ampullate Spidroin Mimics. PLoS One 12(5): E0178201. DOI: 10.1371/journal.pone.0178201